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Tay-Sachs, Canavan, GM1 and Sandhoff diseases

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Yes, it’s important to remember that anyone could be a carrier for Tay-Sachs disease. You are at risk of being a carrier of a Jewish mutation based on your Jewish ancestry. Individuals of Irish, Cajun, French Canadian, and Pennsylvania Dutch descent are also at increased risk of having a Tay-Sachs disease mutation. It may be a good idea for you to have an expanded panel that includes screening for other recessive conditions. Discuss your options with your genetics professional prior to testing.