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Tay-Sachs, Canavan, Sandhoff, GM1 and related diseases

Mouse model

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Term Definition
Mouse model

A laboratory mouse useful for medical research because it has specific characteristics that resemble a human disease or disorder. Strains of mice having natural mutations similar to human ones may serve as models of such conditions. Scientists can also create mouse models by transferring new genes into mice or by inactivating certain existing genes in them. Definition from: National Human Genome Research Institute (

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