Leading the Fight to treat and cure
Tay-Sachs, Canavan, Sandhoff, GM1 and related diseases

Riley's Eighth Birthday!!!


Riley is a very sweet boy who is the center of his family's world and his sister's best friend. Despite all that Canavan disease does to him, he still has the most contagious smile that brightens anyone's day. 

We want to bring smiles to other families, so we ask you to make a donation in honor of Riley's birthday this year!

Thank you!!!


Make a Gift

What is Canavan?

Canavan is a progressive neurological genetic disorder caused by the absence of a vital enzyme known as aspartoacylase (ASPA). ASPA breaks N-acetylaspartate acid (NAA) into building blocks essential for building myelin. Myelin is a fatty membrane (also known as white matter) that forms a proactive coating around each nerve ensuring the nerve functions properly.  It is one of over 50 genetically inherited disorders known as Leukodystrophies Diseases.

What about research?

To date, there is no treatment or cure for Canavan disease but research is making exciting advances towards a treatment and a cure.  Research includes gene therapy, stem cell therapy and acetate supplement.

Read more about the Research We Fund here.